Journal of Toxicology

Research Article

Clinical Validation of a Highly Sensitive GC-MS Platform for Routine Urine Drug Screening and Real-Time Reporting of up to 212 Drugs

Table 2

List of drugs identified by the five platform configurations for three patient specimens. More drugs were detected by the new platform compared to the reference platform and the mixed configurations.
 Reference platformReference GC-MS with AMDIS and old spectral libraryReference GC-MS with AMDIS and new spectral libraryNew GC-MS with old spectral library New platform
Patient 1AcetaminophenAcetaminophenAcetaminophenAcetaminophenAcetaminophen
CaffeineCaffeineCaffeineCaffeineCaffeine
VenlafaxineVenlafaxineVenlafaxineVenlafaxineVenlafaxine
CodeineCodeineCodeineCodeineCodeine
TrimethoprimTrimethoprimTrimethoprimTrimethoprimTrimethoprim
  GabapentinMorphine Gabapentin
   Trazodone Morphine
   Theophylline Trazodone
Patient 2 NicotineNicotineNicotineNicotineNicotine
CotinineCotinineCotinineCotinineCotinine
CaffeineCaffeineCaffeineCaffeineCaffeine
DiphenhydramineDiphenhydramineDiphenhydramineDiphenhydramineDiphenhydramine
   Cocaine Cocaine
Patient 3OxycodoneOxycodoneOxycodoneOxycodoneOxycodone
MethadoneMethadoneMethadoneMethadoneMethadone
TheophyllineTheophyllineTheophyllineTheopyllineTheophylline
GabapentinGabapentinGabapentin Gabapentin
CaffeineCaffeineCaffeineCaffeineCaffeine
  ParaxanthineParaxanthineParaxanthine
   Morphine Morphine