Table of Contents Author Guidelines Submit a Manuscript
Journal of Toxicology
Volume 2013, Article ID 514068, 6 pages
http://dx.doi.org/10.1155/2013/514068
Research Article

In Silico Risk Assessment of HLA-A*02:06-Associated Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis Caused by Cold Medicine Ingredients

1Basic Medical Science and Molecular Medicine, Tokai University School of Medicine, 147 Shimokasuya, Isehara, Kanagawa 259-1143, Japan
2Department of Human Genetics, School of International Health, Graduate School of Medicine, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-0033, Japan
3Department of Ophthalmology, Kyoto Prefectural University of Medicine, Hirokoji Kawaramachi, Kamigyo-ku, Kyoto 602-0841, Japan

Received 12 July 2013; Revised 4 September 2013; Accepted 4 September 2013

Academic Editor: Anthony DeCaprio

Copyright © 2013 Hideto Isogai et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [9 citations]

The following is the list of published articles that have cited the current article.

  • Chao Yang, Congcong Wang, Shilei Zhang, Jian Huang, and Peng Zhou, “Structural and energetic insights into the intermolecular interaction among human leukocyte antigens, clinical hypersensitive drugs and antigenic peptides,” Molecular Simulation, pp. 1–11, 2014. View at Publisher · View at Google Scholar
  • Chie Sotozono, Mayumi Ueta, Eiji Nakatani, Amane Kitami, Hideaki Watanabe, Hirohiko Sueki, Masafumi Iijima, Michiko Aihara, Zenro Ikezawa, Yukoh Aihara, Yoko Kano, Tetsuo Shiohara, Mikiko Tohyama, Yuji Shirakata, Hideaki Kaneda, Masanori Fukushima, Shigeru Kinoshita, and Koji Hashimoto, “Predictive Factors Associated With Acute Ocular Involvement in Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis,” American Journal of Ophthalmology, 2015. View at Publisher · View at Google Scholar
  • Tingting Gao, and Qin Long, “Recent progress in research of pathogeneses of Stevens-Johnson syndrome and toxic epidermal necrolysis,” Chinese Journal of Ophthalmology, vol. 52, no. 9, pp. 708–713, 2016. View at Publisher · View at Google Scholar
  • Okoniewska, Okoniewski, and Grabowski, “Relationship between Tregitopes Structure and Binding with Major Histocompatibility Complex Class i,” Drug Research, vol. 66, no. 4, pp. 211–216, 2016. View at Publisher · View at Google Scholar
  • Peter Schotland, Alexander Zien, Lawrence J. Lesko, Niels Bojunga, and Mirjam Nadine Trame, “Improving drug safety with a systems pharmacology approach,” European Journal of Pharmaceutical Sciences, vol. 94, pp. 84–92, 2016. View at Publisher · View at Google Scholar
  • Noriaki Hirayama, “Docking simulations between drugs and HLA molecules associated with idiosyncratic drug toxicity,” Drug Metabolism and Pharmacokinetics, vol. 32, no. 1, pp. 31–39, 2017. View at Publisher · View at Google Scholar
  • Toru Usui, and Dean J. Naisbitt, “Human leukocyte antigen and idiosyncratic adverse drug reactions,” Drug Metabolism and Pharmacokinetics, vol. 32, no. 1, pp. 21–30, 2017. View at Publisher · View at Google Scholar
  • Kerry A. Ramsbottom, Daniel F. Carr, Andrew R. Jones, and Daniel J. Rigden, “Critical assessment of approaches for molecular docking to elucidate associations of HLA alleles with adverse drug reactions,” Molecular Immunology, vol. 101, pp. 488–499, 2018. View at Publisher · View at Google Scholar
  • Passara Jongkhajornpong, Kaevalin Lekhanont, Phattrawan Pisuchpen, Patchima Chantaren, Vilavun Puangsricharern, Pinnita Prabhasawat, Kanya Suphapeetiporn, Shigeru Kinoshita, and Mayumi Ueta, “Association between HLA-B*44:03-HLA-C*07:01 haplotype and cold medicine-related Stevens-Johnson syndrome with severe ocular complications in Thailand,” British Journal of Ophthalmology, pp. bjophthalmol-2017-311823, 2018. View at Publisher · View at Google Scholar