Effect of Aqueous Stem Bark Extract of Khaya senegalensis on Some Biochemical, Haematological, and Histopathological Parameters of Rats

Table 1

Effect of subchronic oral administration of aqueous stem bark extract of K. senegalensis on ratio of organ weight : body weight of rats and percentage change in body weight of the first day and last day of the experimental period.

Dose mg/kg bw	Kidney : body weight	Liver : body weight	Heart : body weight	Spleen : body weight	Change in body weight (%)
0	0.0053±0.0001	0.0348±0.0017	0.0028±0.0005	0.0026±0.0001	62.64±8.5
400	0.0057±0.0003	0.0365±0.0016	0.0029±0.0008	0.0028±0.0004	47.11±4.8^b
800	0.0051±0.0002	0.0365±0.0013	0.0030±0.0006	0.0030±0.0003	43.39±13.1^b
1200	0.0052±0.0003	0.0366±0.0016	0.0030±0.0006	0.0033±0.0005	41.84±3.4^b
1600	0.0057±0.0003	0.0383±00.0012^b	0.0031±0.0004	0.0034±0.0005	37.45±4.8^b
2000	0.0055±0.0004	0.0398±0.0017^b	0.0031±0.0005	0.0043±0.0001^b	35.32±9.9^b

Values are expressed as mean ± SD; 𝑛=5. The level of significance was set at ^b𝑃<0.05 when compared with control at 0 mg/kg body weight, Dunnett’s multiple comparison test.