Effect of Aqueous Stem Bark Extract of Khaya senegalensis on Some Biochemical, Haematological, and Histopathological Parameters of Rats

Table 2

Effect of subchronic oral administration of aqueous stem bark extracts of K. senegalensis on kidney function parameters of rats.

Dose mg/kg bw	Urea (mmol/L)	Creatinine	Na^+ (mmol/L)	K^+ (mmol/L)
0	3.83±0.38	14.47±1.74	134.3±1.48	4.38±0.08
400	4.87±0.69^b	13.45±3.02	135.5±1.96	4.48±0.08^b
800	4.92±0.29^b	22.74±3.46	136.9±1.86	5.16±0.24^b
1200	4.89±0.37^b	29.11±3.10	136.8±2.38	5.48±0.30^b
1600	5.07±0.16^b	49.44±9.42^b	140.8±4.55^b	5.58±0.41^b
2000	5.02±0.20^b	70.46±10.99^b	142.8±4.10^b	6.21±0.24^b

Values are expressed as mean ± SD; 𝑛=5. The level of significance was set at ^b𝑃<0.05 when compared with control at 0 mg/kg body weight, Dunnett’s multiple comparison test.