Effect of the Antibiotic Neomycin on the Toxicity of the Glycoside Vicine in Rats

Table 2

The effect of vicine and neomycin on some hematological parameters in rats.

Parameters	Group
	Control; (1 mL saline)	Vicine; (400 mg/kg)	Neomycin (250 mg/kg); + Vicine (400 mg/kg)
Hb (gm/dL)	13.88±0.26	9.78±2.24^∗	12.92±0.55^a
Hct (%)	42.63±1.22	30.21±3.92^∗∗	39.85±2.24^b
RBCs (10^6 cells/mm^3)	5.82±0.35	3.83±0.13^∗∗∗	5.24±0.75^b
WBCs (10^3 cells/mm^3)	8.95±0.55	7.85±1.23	9.74±2.56

Results were expressed as mean±SD and significant difference according to control group at 𝑃≤0.05, ANOVA showed a highly significant difference between all groups at 𝑃≤0.0001.^∗𝑃≤0.05 significant difference compared to control, ^∗∗𝑃≤0.01 highly significant difference compared to control. ***Very highly significant at 𝑃≤0.001.^a𝑃≤0.05 significant difference compared to vicine. ^b𝑃≤0.01 highly significant difference compared to vicine.