Effect of the Antibiotic Neomycin on the Toxicity of the Glycoside Vicine in Rats

Table 3

Effect of vicine and neomycin on serum glucose, blood GSH, serum TBARs and serum G6-PD in rats.

Parameters	Group
	Control; (1 mL saline)	Vicine; (400 mg/kg)	Neomycin (250 mg/kg); + Vicine (400 mg/kg)
Serum glucose (mg/dL)	104.51±15.25	82.63±6.12^∗	103.25±14.32^a
Blood GSH (mg/dL)	35.12±1.61	21.66±3.63^∗∗	31.62±3.12^b
Serum TBARs (nmol/dL)	16.22±2.46	28.13±3.62^∗∗∗	19.52±3.51^b
Serum G6-PD (U/L)	32.22±3.58	17.53±2.61^∗∗	29.91±4.81^b

Results were expressed as mean±SD and significant difference according to control group at 𝑃≤0.05, ANOVA showed a highly significant difference between all groups at 𝑃≤0.0001.^∗𝑃≤0.05 significant difference compared to control, ^∗∗𝑃≤0.01 highly significant difference compared to control. ***Very highly significant at 𝑃≤0.001 compared to control. ^a𝑃≤0.05 significant difference compared to vicine. ^b𝑃≤0.01 highly significant difference compared to vicine.