Effect of the Antibiotic Neomycin on the Toxicity of the Glycoside Vicine in Rats

Table 4

The effect of vicine and neomycin on serum total protein, albumin, globulin, and total protein in liver tissue in rats.

Parameters	Group
	Control; (1 mL saline)	Vicine; (400 mg/kg)	Neomycin (250 mg/kg); + Vicine (400 mg/kg)
Serum total protein (g/dL)	8.57±0.54	6.28±0.55^∗∗	8.29±0.25^b
Serum albumin (g/dL)	5.12±0.51	4.95±0.82	4.86±0.52
Serum globulin (g/dL)	3.45±0.32	1.06±0.95^∗∗	3.43±0.65^b
Liver total protein (g/g tissue)	3.25±0.81	1.72±0.55^∗	3.12±0.25^a

Results were expressed as mean±SD and significant difference according to control group at 𝑃≤0.05, ANOVA showed a highly significant difference between all groups at 𝑃≤0.0001.^∗𝑃≤0.05 significant difference compared to control, ^∗∗𝑃≤0.01 highly significant difference compared to control. ^a𝑃≤0.05 significant difference compared to vicine. ^b𝑃≤0.01 highly significant difference compared to vicine.