In Vitro Toxicity Evaluation of Engineered Cadmium-Coated Silica Nanoparticles on Human Pulmonary Cells

Figure 6

Histograms show the number of colonies formed after 10 consecutive days exposure to increasing concentrations of Cd-SiO₂NPs, CdCl₂, SiO₂NPs at the doses indicated in the figure. The formation of A549 colonies appeared to be serious compromised by both Cd-SiO₂NP and CdCl₂ treatments already at the lowest dose of 0.05 μg/mL, while SiO₂NPs had no effects on their formation. Data are mean ± DS of two separate experiments each carried out in three replicates, expressed as percentage of control colonies. *𝑃<0.05 significant difference from control. Error bars: ±SD.