Research Article
Differential Cytotoxicity Responses by Dog and Rat Hepatocytes to Phospholipogenic Treatments
Table 1
Cell survival IC50 (half maximal inhibitory concentration) values of dog and rat hepatocytes treated with phospholipogenic or nonphospholipogenic compounds. Cells were fixed with formaldehyde/Hoescht, and survival was quantified using the Cellomics Arrayscan instrument (see Materials and Methods). Isolates were obtained on different days. The data are represented as individual experiments only ( = 1 or 2) or as an average of 3 individual (separate isolates, = 3) experiments ± SD.
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Statistically significant (P < 0.05, t-test) differences observed in species’ response. |