Conditioned Medium Reconditions Hippocampal Neurons against Kainic Acid Induced Excitotoxicity: An In Vitro Study

Figure 1

Neuromorphological alteration. Representative photomicrographes demonstrating the morphology of H3 cells in different treatment groups. Kainic acid treatment to H3 cells resulted in prominent decrease in cell density and neurites. In contrast, KA + CM group demonstrated healthy cell bodies with dense neurites. Scale Bar 100 μm. Normal control (NC), normal control exposed to HEK conditioned medium (CM), Kainic acid alone treated (KA), and Kainic acid and HEK conditioned medium cotreated (KA + CM).