Clinical Study
Acute Methotrexate Ingestions in Adults: A Report of Serious Clinical Effects and Treatments
Table 2
Therapies reported for acute methotrexate ingestions in adults as reported to six poison centers (
).
| Therapy | Number of patients | Percentage of patients |
| Any treatment | 24 | 54% | No treatment | 20 | 46 | Dilute irrigation/wash | 14 | 22.2 | IV fluids | 11 | 18 | Cathartic | 10 | 16 | Charcoal-one dose | 9 | 14.3 | Folinic acid | 9 | 14.3 | Lavage | 5 | 8 | Charcoal-multiple doses | 3 | 4.8 | Sodium bicarbonate | 3 | 4.8 | N-acetyl cysteine (oral) | 3 | 4.8 | Antiemetics | 2 | 3.2 | Hemodialysis | 0 | 0 |
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