Acute Methotrexate Ingestions in Adults: A Report of Serious Clinical Effects and Treatments

Table 2

Therapies reported for acute methotrexate ingestions in adults as reported to six poison centers (𝑁=44).

Therapy	Number of patients	Percentage of patients
Any treatment	24	54%
No treatment	20	46
Dilute irrigation/wash	14	22.2
IV fluids	11	18
Cathartic	10	16
Charcoal-one dose	9	14.3
Folinic acid	9	14.3
Lavage	5	8
Charcoal-multiple doses	3	4.8
Sodium bicarbonate	3	4.8
N-acetyl cysteine (oral)	3	4.8
Antiemetics	2	3.2
Hemodialysis	0	0