Impairment of Hepatic and Renal Functions by 2,5-Hexanedione Is Accompanied by Oxidative Stress in Rats

Table 1

Body weights and organ weights of rats exposed to 2,5-hexanedione for 21 days.

	Control	0.25% 2,5-HD	0.50% 2,5-HD	1.0% 2,5-HD
Body weight gain (g)	31.56 ± 6.64	12.81 ± 4.54*	3.71 ± 0.04*	1.07 ± 3.48*
RLW (g/100 g bw)	2.27 ± 0.13	2.31 ± 0.11	2.56 ± 0.89*	2.75 ± 0.93*
RKW (g/100 g bw)	0.53 ± 0.08	0.54 ± 0.07	0.59 ± 0.04*	0.71 ± 0.08*

RLW: relative liver weight; RKW: relative kidney weight. The data are expressed as mean ± SD for eight animals per group. * < 0.05 against control.