Journal of Toxicology / 2014 / Article / Fig 4

Research Article

Proliferation and 1/2 Cytokine Production in Human Peripheral Blood Mononuclear Cells after Treatment with Cypermethrin and Mancozeb In Vitro

Figure 4

cytokine profiles. Effect on cytokines IL-4, IL-6, and IL-10 production in PBMC cultures. Mancozeb: (a) IL-4; (b) IL-6; and (c) IL-10. Cypermethrin: (d) IL-4; (e) IL-6; and (f) IL-10. Values shown are mean (±SE) from triplicate samples conducted with PBMC from three volunteers. *; ** versus zero control. For each donor, statistical analyses performed across the doses showed that resultant IL-6 values were consistently significantly different as a function of dose in the mancozeb study. Further, in that same study, IL-10 values were also consistently significantly different as a function of dose for doses of ≥0.93 μM.

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