Antigenotoxic Effect of Curcumin and Carvacrol against Parathion Induced DNA Damage in Cultured Human Peripheral Blood Lymphocytes and Its Relation to GSTM1 and GSTT1 Polymorphism

Table 4

Combined effect of curcumin and carvacrol against parathion treated cultured human peripheral blood lymphocytes.

Treatments	Concentrations used (g/mL + g/mL)	Metaphase scored	SCE/cell ± SE
Control	Untreated	50
Parathion	2.5	50
Parathion + curcumin	2.5 + 10	50
Parathion + curcumin	2.5 + 15	50
Parathion + carvacrol	2.5 + 2.5	50
Parathion + carvacrol	2.5 + 5.0	50
Parathion + curcumin + carvacrol	2.5 + 10 + 2.5	50
Parathion + curcumin + carvacrol	2.5 + 15 + 5.0	50

(significance as compared to untreated).
(significant as compared to parathion treatment).
(nonsignificant as compared to curcumin and carvacrol alone treatment).