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Journal of Toxicology
Volume 2014, Article ID 413870, 5 pages
http://dx.doi.org/10.1155/2014/413870
Research Article

Concentration of Cd, Pb, Hg, and Se in Different Parts of Human Breast Cancer Tissues

1Environmental Forensic Laboratory, Department of Environmental Sciences, Faculty of Natural Resource and Marine Science, Tarbiat Modares University, P.O. Box 64414-356, Noor, Mazandaran, Iran
2Faculty of Marine Science, Tarbiat Modares University, Tehran, Iran

Received 16 July 2013; Revised 5 December 2013; Accepted 18 December 2013; Published 11 February 2014

Academic Editor: Orish Ebere Orisakwe

Copyright © 2014 Mehrnoosh Mohammadi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Breast cancer is the major cause of cancer morbidity and mortality between women in the world. Metals involved in environmental toxicology are closely related to tumor growth and cancer. On the other hand, some metals such as selenium have anticarcinogenic properties. The aim of this study is to determine the concentration of cadmium, lead, mercury, and selenium in separated parts of tegmen, tumor, tumor adiposity, and tegmen adiposity of 14 breast cancer tissues which have been analyzed by graphite furnace atomic absorption (AA-670) and ICP-OES (ULTIMA 2CE). Our results show that Se and Hg have maximum and minimum concentration, respectively. Statistical analysis reveals no significant differences between metal accumulations in different parts of cancer tissues and this observation might be due to the close relation of separated parts of fatty breast organ. Thus, we could conclude that a high level of these heavy metals is accumulated in Iranian cancerous breasts and their presence can be one of the reasons of cancer appearance.