Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS
Figure 4
Effect of sildenafil on endothelial nitric oxide synthase (eNOS) immunohistochemical staining of gentamicin-treated rat kidney (×1000). Localization of eNOS immunoreactivity in the kidney cortex of (a) and (b) control and sildenafil-treated groups, respectively, showing positive immunoreactivity in the glomerulus endothelium (arrow), (c) gentamicin-treated group showing absent immunoreactivity within the renal glomerulus (G), and (d) gentamicin and sildenafil-treated group showing immunoreactivity within the renal glomerulus (arrow).
