Sildenafil Ameliorates Gentamicin-Induced Nephrotoxicity in Rats: Role of iNOS and eNOS

Table 1

Effect of sildenafil on serum creatinine and urea as well as urinary albumin levels of gentamicin-induced nephrotoxicity in rats.

Group	Creatinine; mg/dL	Urea; mg/dL	Albumin; mg/dL
Control	0.53±0.01	26.2±0.24	0.36±0.01
Sildenafil	0.55±0.01	25.8±0.17	0.34±0.01
Gentamicin	3.1±0.1^∗∘	139±1.48^∗∘	4.05±0.10^∗∘
Gentamicin + sildenafil	0.94±0.01^∗∘×	59.6±1.02^∗∘×	2.04±0.06^∗∘×

Data are mean ± SEM of 6–8 rats. ^*,°,×Significantly different from control, sildenafil, and gentamicin groups, respectively, at 𝑃<0.05.