Journal of Toxicology / 2014 / Article / Tab 1

Research Article

Chlorogenic and Caftaric Acids in Liver Toxicity and Oxidative Stress Induced by Methamphetamine

Table 1

Effect of chlorogenic and caftaric acids on serums AST, ALT, total bilirubin, and ALP of METH-injected rats.

Groups Parameters
AST
(U/L)
ALT
(U/L)
Total bilirubin
(mg/dL)
ALP
(U/L)

Control123.1 ± 3.8562.5 ± 2.480.56 ± 0.08210.5 ± 6.81
METH group140.2 ± 0.72*82.0 ± 1.96**0.75 ± 0.05**241.2 ± 7.15**
Chlorogenic acid + METH group125.4 ± 4.17a60.1 ± 2.9b0.58 ± 0.04b215.1 ± 6.59b
Caftaric acid + METH group128.3 ± 3.94a65.0 ± 2.87b0.60 ± 0.07a223.0 ± 4.86a

Data presented as mean ± SE. Number of animals = 8 per group.
*Significant change compared to control rats.
**Highly significant change compared to control rats.
aSignificant change compared to METH group.
bHighly significant change compared to METH group.