Journal of Toxicology / 2014 / Article / Tab 2

Research Article

Chlorogenic and Caftaric Acids in Liver Toxicity and Oxidative Stress Induced by Methamphetamine

Table 2

Effect of chlorogenic and caftaric acids on serum total protein, albumin, globulin, and albumin/globulin ratio of METH-injected rats.

Groups Parameters
Total protein
(g/dL)
Albumin
(g/dL)
Globulin
(g/dL)
Alb/glob.
ratio

Control7.64 ± 0.723.76 ± 0.453.88 ± 0.250.97 ± 0.05
METH group6.10 ± 0.35*2.81 ± 0.17*3.29 ± 0.17*0.85 ± 0.03*
Chlorogenic acid + METH group8.16 ± 0.93a3.96 ± 0.48a4.18 ± 0.18b0.95 ± 0.04a
Caftaric acid + METH group7.75 ± 0.68a3.86 ± 0.65a3.89 ± 0.25a0.90 ± 0.07

Data presented as mean ± SE. Number of animals = 8 per group.
*Significant change compared to control rats.
**Highly significant change compared to control rats.
aSignificant change compared to METH group.
bHighly significant change compared to METH group.