Chlorogenic and Caftaric Acids in Liver Toxicity and Oxidative Stress Induced by Methamphetamine

Table 2

Effect of chlorogenic and caftaric acids on serum total protein, albumin, globulin, and albumin/globulin ratio of METH-injected rats.

Groups	Parameters
	Total protein; (g/dL)	Albumin; (g/dL)	Globulin; (g/dL)	Alb/glob.; ratio
Control	7.64 ± 0.72	3.76 ± 0.45	3.88 ± 0.25	0.97 ± 0.05
METH group	6.10 ± 0.35*	2.81 ± 0.17*	3.29 ± 0.17*	0.85 ± 0.03*
Chlorogenic acid + METH group	8.16 ± 0.93^a	3.96 ± 0.48^a	4.18 ± 0.18^b	0.95 ± 0.04^a
Caftaric acid + METH group	7.75 ± 0.68^a	3.86 ± 0.65^a	3.89 ± 0.25^a	0.90 ± 0.07

Data presented as mean ± SE. Number of animals = 8 per group.
*Significant change (𝑃≤0.05) compared to control rats.
**Highly significant change (𝑃≤0.01) compared to control rats.
^aSignificant change (𝑃≤0.05) compared to METH group.
^bHighly significant change (𝑃≤0.01) compared to METH group.