Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model

Table 3

L-BMAA concentrations (μg/g) in brains and livers of mice as detected by UPLC-UV. Each value is the mean of three replicates ± standard deviation. BW: body weight; F: female; M: male. A, B, and E: mice treated (0.03, 0.3, and 3 mg/g BW) groups.

L-BMAA dose (mg/g BW)	Gender	L-BMAA (µg/g) in brain	L-BMAA (µg/g) in liver
Control (0)	F	0.00 ± 0.00	0.00 ± 0.00
	M	0.00 ± 0.00	0.00 ± 0.00
(A) 0.03	F	0.06 ± 0.03	0.05 ± 0.01
	M	0.28 ± 0.05	0.10 ± 0.01
(B) 0.30	F	0.16 ± 0.02	0.14 ± 0.05
	M	1.83 ± 0.69	1.15 ± 0.04
(E) 3.00	F	2.45 ± 0.33	1.80 ± 0.09
	M	4.49 ± 0.21	2.35 ± 0.30