Acute β-N-Methylamino-L-alanine Toxicity in a Mouse Model

Table 4

L-BMAA concentrations (μg/g) in brains and livers of mice as detected by LC/MS/MS chromatography. Each value is the mean of three replicates ± standard deviation. BW: body weight; F: female; M: male. A, B, and E: mice treated (0.03, 0.3, and 3 mg/g BW) groups.

L-BMAA dose (mg/g BW)	Gender	L-BMAA (µg/g) in brain	L-BMAA (µg/g) in liver
Control (0)	F	0.00 ± 0.00	0.00 ± 0.00
	M	0.00 ± 0.00	0.00 ± 0.00
(A) 0.03	F	1.61 ± 0.41	1.12 ± 0.10
	M	3.34 ± 0.52	1.53 ± 0.21
(B) 0.30	F	4.69 ± 0.34	2.64 ± 0.28
	M	8.41 ± 0.56	3.85 ± 0.22
(E) 3.00	F	21.79 ± 0.92	11.94 ± 0.64
	M	32.62 ± 0.99	15.59 ± 0.57