Journal of Toxicology / 2016 / Article / Tab 6

Research Article

A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine

Table 6

Summary of feed efficiency.

Group (mg/kg bw/d)Feed efficiency (g bw/g food)Sum
Days0–77–1414–2121–2828–3535–4242–4949–5656–6363–7070–7777–8484–890–89
Weeks123456789101112131–13

Males
 ControlMean0.260.150.150.120.080.100.090.070.050.060.050.030.020.10
SD0.020.020.020.020.010.020.020.020.010.010.020.020.020.01
 180Mean0.240.160.140.120.100.090.080.080.060.040.050.040.040.09
SD0.030.010.020.030.030.020.020.020.020.020.020.020.010.01
SS
 300Mean0.210.150.130.120.090.090.080.070.060.060.070.020.050.09
SD0.050.050.030.030.020.020.020.010.020.020.020.020.040.01
SS
 375Mean0.150.140.140.110.080.070.070.070.050.060.070.040.060.09
SD0.080.070.050.050.030.030.040.040.030.020.030.020.020.01
SS

Females
 ControlMean0.200.130.100.080.080.050.050.050.020.050.050.030.040.07
SD0.020.020.020.030.030.020.020.020.020.010.030.020.020.01
 180Mean0.200.150.110.090.070.040.050.060.020.040.050.050.060.07
SD0.040.040.040.030.030.030.030.020.010.020.020.030.030.01
SS
 300Mean0.200.140.130.100.070.060.060.040.060.020.060.030.030.07
SD0.040.040.030.030.020.020.030.020.020.020.020.020.020.01
SS
 375Mean0.180.180.100.110.080.070.070.040.040.040.060.040.070.07
SD0.020.040.040.030.030.020.040.020.020.010.030.020.030.01
SS

±%, percent deviation versus control; mg/kg bw/d, milligrams per kilogram body weight per day; g bw/g food, grams body weight per grams of food; SD, standard deviation; g, grams; SS, statistical significance; , number of animals.
< 0.05; < 0.01.