Research Article

Screening of Pesticides with the Potential of Inducing DSB and Successive Recombinational Repair

Table 3

Cytotoxic effect of pesticides and metabolites that induced double-strand breaks.

CompoundSurvival range (%)R2Fp value

PesticideGlyphosate100 to 700.2529.4310.0047
Permethrin100 to 1000.0063860.064270.8050
Pentachlorophenol100 to 780.0070.0920.7669

MetaboliteEndosulfan lactone100 to 600.678725.350.0003
Paraoxon98 to 900.14732.2460.1579

Positive controlEtoposide100 to 960.9934

Linear regression; the positive control was not cytotoxic at the concentration tested, 50 µM.