Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine

Table 2

Effects of Quercetin in comparison to DFO on small intestinal iron levels in iron overloaded rats.

Groups	Duodenum iron level(mg/g wet weight) ± SE	Jejunum iron level(mg/g wet weight) ± SE	Ilieum iron level (mg/g wet weight) ± SE
Control	0.055±0.0005	0.0361±0.0001	0.0267±0.0002
DFO	0.0533±0.0005	0.0359±0.0000	0.0266±0.0001
Quercetin	0.0551±0.0004	0.0361±0.0001	0.0268±0.0001
Iron	0.0881±0.0009 a	0.0563±0.0004 a	0.1348±0.0002 a
Iron + DFO	0.0611±0.0005 b	0.0365±0.0001 b	0.0282±0.0003 b
Iron+Quercetin	0.0617±0.0004 b,c	0.0369±0.0002 b,c	0.0287±0.0005 b,c
P-Value	0.001	0.001	0.001
LSD 0.05	0.0016	5.478 × 10^−4	7.164 × 10^−4

Values are expressed as means ±standard error (n=6), LSD: least significance difference, DFO: deferoxamine.
a: highly significant difference as compared to control group (P< 0.001).
b: highly significant difference as compared to iron overload group (P< 0.001).
c: nonsignificant difference as compared to iron + DFO group (P > 0.05).