Ameliorating Iron Overload in Intestinal Tissue of Adult Male Rats: Quercetin vs Deferoxamine

Table 3

Effects of Quercetin in comparison to DFO on serum oxidative stress and total antioxidant capacity in iron overloaded rats.

Groups	MDA; (mM/L) ± SE	TAC; (nmol/ml) ± SE
Control	10.86 ± 0.09	1.34 ± 0.02
DFO	10.50 ± 0.15	1.36 ± 0.01
Quercetin	10.44 ± 0.14	1.37 ± 0.01
Iron	34.2 ± 0.59 a	0.53 ± 0.01 a
Iron + DFO	12.74 ± 0.59 b	1.31 ± 0.05 b
Iron+Quercetin	11.77 ± 0.74 b,c	1.27 ± 0.04 b,c
P-Value	0.001	0.001
LSD 0.05	1.3356	0.0804

Values are expressed as means ± standard error (n=6), LSD: least significance difference, DFO: Deferoxamine, MDA: malonyldialdehyde, and TAC: total antioxidant capacity.
a: highly significant difference as compared to control group (P< 0.001).
b: highly significant difference as compared to iron overload group (P< 0.001).
c: non- significant difference as compared to iron + DFO group (P > 0.05).