Potential Toxicity of the Essential Oil from Minthostachys mollis: A Medicinal Plant Commonly Used in the Traditional Andean Medicine in Peru

Table 1

Effect of Minthostachys mollis essential oil (Mm-EO) on the relative weight of the organs in treated rats for 28 days.

Organ	Control	Mm-EO 100	Mm-EO 250	Mm-EO 500
Males
Heart	0.32 ± 0.01	0.33 ± 0.05	0.36 ± 0.09	0.49 ± 0.07
Lungs	0.70 ± 0.12	0.73 ± 0.14	0.88 ± 0.14	1.10 ± 0.15
Liver	3.10 ± 0.17	3.21 ± 0.10	3.79 ± 0.09	4.90 ± 0.30
Spleen	0.35 ± 0.04	0.38 ± 0.11	0.41 ± 0.08	0.48 ± 0.04
Stomach	0.52 ± 0.08	0.55 ± 0.21	0.68 ± 0.29	1.12 ± 0.18
Kidney	0.37 ± 0.07	0.39 ± 0.09	0.46 ± 0.06	0.55 ± 0.11
Testis	0.92 ± 0.12	0.96 ± 0.14	1.20 ± 0.30	1.63 ± 0.11
Females
Heart	0.32 ± 0.11	0.35 ± 0,09	0.41 ± 0.14	0.73 ± 0.11
Lungs	0.95 ± 0.09	1.09 ± 0.14	1.25 ± 0.17	1.95 ± 0.21
Liver	2.90 ± 0.27	3.10 ± 0.11	3.73 ± 0.15	4.96 ± 0.23
Spleen	0.39 ± 0.10	0.42 ± 0.08	0.45 ± 0.12	0.68 ± 0.23
Stomach	0.50 ± 0.07	0.63 ± 0.15	0.82 ± 0.21	1.07 ± 0.27
Kidney	0.32 ± 0.04	0.34 ± 0.05	0.41 ± 0.10	0.66 ± 0.11
Uterus	0.47 ± 0.05	0.50 ± 0.10	0.59 ± 0.14	0.91 ± 0.09

Values are expressed as Mean ± SD, significance when compared with control (). One-way ANOVA followed by Tukey test.