Journal of Toxicology / 2019 / Article / Tab 1

Research Article

Potential Toxicity of the Essential Oil from Minthostachys mollis: A Medicinal Plant Commonly Used in the Traditional Andean Medicine in Peru

Table 1

Effect of Minthostachys mollis essential oil (Mm-EO) on the relative weight of the organs in treated rats for 28 days.

OrganControlMm-EO 100Mm-EO 250Mm-EO 500

Males
Heart0.32 ± 0.010.33 ± 0.050.36 ± 0.090.49 ± 0.07
Lungs0.70 ± 0.120.73 ± 0.140.88 ± 0.141.10 ± 0.15
Liver3.10 ± 0.173.21 ± 0.103.79 ± 0.094.90 ± 0.30
Spleen0.35 ± 0.040.38 ± 0.110.41 ± 0.080.48 ± 0.04
Stomach0.52 ± 0.080.55 ± 0.210.68 ± 0.291.12 ± 0.18
Kidney0.37 ± 0.070.39 ± 0.090.46 ± 0.060.55 ± 0.11
Testis0.92 ± 0.120.96 ± 0.141.20 ± 0.301.63 ± 0.11

Females
Heart0.32 ± 0.110.35 ± 0,090.41 ± 0.140.73 ± 0.11
Lungs0.95 ± 0.091.09 ± 0.141.25 ± 0.171.95 ± 0.21
Liver2.90 ± 0.273.10 ± 0.113.73 ± 0.154.96 ± 0.23
Spleen0.39 ± 0.100.42 ± 0.080.45 ± 0.120.68 ± 0.23
Stomach0.50 ± 0.070.63 ± 0.150.82 ± 0.211.07 ± 0.27
Kidney0.32 ± 0.040.34 ± 0.050.41 ± 0.100.66 ± 0.11
Uterus0.47 ± 0.050.50 ± 0.100.59 ± 0.140.91 ± 0.09

Values are expressed as Mean ± SD, significance when compared with control (). One-way ANOVA followed by Tukey test.