Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Table 3
The effects of different concentrations of methanolic extract of pomelo on the percentage of water content of different organs.
Organs
Control
250 mg/kg
500 mg/kg
1000 mg/kg
Heart
73.00 ± 2.30
72.05 ± 2.08
76.68 ± 2.07
76.08 ± 1.64
Kidney
73.47 ± 2.07
74.18 ± 3.05
72.34 ± 2.50
73.03 ± 1.99
Lung
71.84 ± 3.92
74.88 ± 4.30
72.55 ± 2.67
72.12 ± 3.81
Liver
65.12 ± 4.00
65.13 ± 2.75
64.48 ± 3.07
64.24 ± 2.66
Spleen
74.61 ± 3.11
75.36 ± 2.79
76.92 ± 2.55
76.92 ± 1.60
Caecum
74.60 ± 2.02
73.72 ± 2.97
74.50 ± 2.92
73.80 ± 3.73
Pancreas
66.23 ± 1.00
65.96 ± 1.32
66.07 ± 3.53
63.83 ± 2.07
Brain
51.70 ± 3.38
54.50 ± 2.85
55.23 ± 2.64
58.00 ± 2.13
Testes
76.33 ± 2.62
77.84 ± 2.32
76.40 ± 1.99
75.57 ± 2.16
Thymus
69.68 ± 2.12
74.80 ± 3.01
68.88 ± 2.12
70.80 ± 1.52
Caput
72.73 ± 2.53
75.84 ± 3.06
75.07 ± 1.89
74.94 ± 1.54
CPG
73.60 ± 3.17
72.93 ± 2.61
76.58 ± 1.66
75.76 ± 1.84
Stomach
76.44 ± 1.38
76.14 ± 0.82
76.30 ± 1.78
76.22 ± 1.63
Ovary
56.85 ± 2.56
55.34 ± 1.53
55.23 ± 2.35
55.93 ± 1.50
FT
76.95 ± 1.68
77.69 ± 2.58
77.13 ± 0.86
75.92 ± 1.89
Results are expressed as mean ± SD (n=8). CPG: Cowper gland and FT: fallopian tube. Nonsignificant changes were found when all treatment groups were compared against the control group (p< 0.05) as determined by using a one-way ANOVA followed by Dunnett’s multiple comparison tests.
