Antioxidant Potential, Subacute Toxicity, and Beneficiary Effects of Methanolic Extract of Pomelo (Citrus grandis L. Osbeck) in Long Evan Rats
Table 6
The effects of different concentrations of pomelo methanolic extract on serum renal markers.
Biochemical parameters
Control
250 mg/kg
500 mg/kg
1000 mg/kg
Creatinine (mmol/L)
39.75 ± 3.09
35.00 ± 5.59
37.25 ± 6.34
34.00 ± 3.80
Urea (mmol/L)
5.30 ± 0.54
4.47 ± 0.69
4.97 ± 1.15
4.32 ± 0.61
Uric acid (mmol/L)
45.50 ± 4.80
38.25 ± 10.40
35.50 ± 9.00
33.25 ± 6.20
Na+ (mmol/L)
141.00 ± 2.58
142.50 ± 4.43
142.50 ± 1.20
142.50 ± 6.40
K+ (mmol/L)
4.12 ± 0.15
4.20 ± 0.08
4.32 ± 0.09
4.05 ± 0.25
Ca2+ (mmol/L)
2.12 ± 0.22
2.22 ± 0.28
2.30 ± 0.81
2.27 ± 0.09
Mg2+(mmol/L)
0.82 ± 0.12
0.82 ± 0.12
0.87 ± 0.09
0.87 ± 0.05
Cl- (mmol/L)
101.50 ± 2.60
102.25 ± 4.34
101.00 ± 1.80
102.25 ± 2.98
PO4- (mmol/L)
2.30 ± 0.29
2.40 ± 0.29
2.47 ± 0.29
2.42 ± 0.09
Results are expressed as mean ± SD (n=8). denotes level of significant difference when compared to the control group as determined using a one-way ANOVA followed by Dunnett’s multiple comparison tests.
