Safety Assessment of Ubiquinol Acetate: Subchronic Toxicity and Genotoxicity Studies

Table 13

Summary of gross necropsy findings, males and females.

Organs	Group and Dose (mg/kg b.w.)
Diagnoses	G1		G1R		G2		G3		G4		G4R
	0		0		150		300		600		600
	TS		TS		TS		TS		TS		TS
	M	F	M	F	M	F	M	F	M	F	M	F
	Liver
No Abnormality Detected	10	10	5	5	10	10	10	10	10	8	5	5
Small white to yellow irregular area, focal	0	0	0	0	0	0	0	0	0	2	0	0
Lungs
No Abnormality Detected	10	10	5	5	10	10	10	10	8	7	5	4
Small yellow foci	0	0	0	0	0	0	0	0	2	3	0	1

Note: the numerical indicated under observation represents the number of animals with and without lesions; M: male; F: female; TS: terminal sacrifice.