Journal of Toxicology / 2019 / Article / Tab 4

Research Article

A Toxicological Evaluation of Mango Leaf Extract (Mangifera indica) Containing 60% Mangiferin

Table 4

Summary of mouse micronucleus test results.

Groupstotal number of PCE analyzed
mg/kg bwSamplingPCE/ PCE+NCEMPCE
n=5time, hoursmean± SDmean± SD

Vehicle control24200000.530.025.001.22
Test item
 50024200000.510.013.800.84
 100024200000.500.015.001.00
 200024200000.490.014.801.79
Positive control24200000.360.06128.64.56
Historical Vehicle Control244000n/an/a4.770.94

MPCE: micronucleated polychromatic erythrocytes; NCE: normochromatic erythrocytes; PCE: polychromatic erythrocytes
Vehicle control: aqua purificata; positive control: 60 mg/kg bw cyclophosphamide
p<0.01
MPCE per 4000 PCE
dosing occurred twice in 24 hours.

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