A Toxicological Evaluation of Germanium Sesquioxide (Organic Germanium)
Table 6
Summary of body weight gain between days (males), 90-day study.
Group‡ mg/kg bw/day
Body weight gain (g) between days
Sum.
0–3
3–7
7–10
10–14
14–17
17–21
21–24
24–28
28–35
35–42
42–49
49–56
56–63
63–70
70–77
77–84
84–89
0–89
Control
Mean
12.4
23.9
6.4
22.3
7.5
19.6
5.2
17.0
20.2
16.4
14.7
13.2
9.2
7.3
10.5
2.8
5.6
214.2
SD
4.0
3.6
5.2
3.4
4.1
3.6
2.0
2.7
3.5
4.8
4.4
3.9
5.3
3.9
5.0
4.0
4.5
28.5
500
Mean
14.6
25.7
7.5
23.1
3.9
20.4
7.8
14.3
18.4
14.2
14.0
14.0
9.3
9.9
6.4
1.3
5.6
210.4
SD
3.1
3.0
3.4
3.5
4.6
3.5
2.2
3.7
4.1
3.0
4.1
4.8
4.7
3.1
5.6
4.3
4.2
16.3
SS
1000
Mean
18.1
24.2
8.4
20.7
7.4
16.3
7.2
10.6
20.3
13.8
12.9
11.8
11.3
6.5
5.5
2.2
7.6
204.8
SD
4.6
7.1
2.8
4.9
3.7
5.5
2.8
4.5
4.9
5.8
4.0
2.9
6.8
4.4
4.7
6.1
3.9
47.7
SS
2000
Mean
15.9
22.4
6.9
19.6
2.0
17.7
4.5
10.3
16.9
10.2
8.6
10.9
10.0
11.6
5.7
5.6
-2.0
176.8
SD
3.4
3.7
2.6
4.8
4.3
3.9
3.2
4.5
5.8
5.8
7.7
4.2
9.4
9.2
12.6
6.1
3.7
23.4
SS
Test for significance
DN
NS
NS
NS
DN
NS
DN
DN
NS
DN
DN
NS
NS
NS
U
NS
DN
U
Abbreviations: DN: Duncan’s multiple range test; NS: not significant; SD: standard deviation; SS: statistical significance; U: Mann–Whitney U-test versus control. ‡n = 10 for all groups. ,.
