A Toxicological Evaluation of Germanium Sesquioxide (Organic Germanium)
Table 7
Summary of feed efficiency (males), 90-day study.
(Group mg/kg bw/day)
Feed efficiency (g food/g bwg)
Days
0–7
7–14
14–21
21–28
28–35
35–42
42–49
49–56
56–63
63–70
70–77
77–84
84–89
0–89
Weeks
1
2
3
4
5
6
7
8
9
10
11
12
13
1–13
Control
Mean
4.84
5.94
6.44
7.43
8.20
10.68
12.05
13.31
30.53
22.14
19.73
49.20
32.23
9.94
SD
0.61
1.03
1.32
0.76
1.43
2.48
3.59
3.43
45.68
11.08
8.06
53.83
35.21
0.79
n†
10
10
10
10
10
10
10
10
9
9
10
6
8
10
500
Mean
4.47
5.71
7.44
7.92
9.38
12.43
13.32
13.09
21.55
18.41
26.83
73.06
34.05
10.32
SD
0.42
0.64
1.90
1.89
2.39
2.72
5.41
3.78
7.57
7.15
15.00
65.90
35.36
0.65
n†
10
10
10
10
10
10
10
10
10
10
8
6
9
10
1000
Mean
4.17
5.95
7.65
9.68
8.29
13.33
14.08
14.73
22.40
28.31
26.18
34.60
16.41
10.49
SD
0.89
1.14
1.97
2.01
1.49
4.12
6.45
4.19
18.82
15.81
9.75
22.24
5.85
1.53
n†
10
10
10
10
10
10
10
10
10
9
8
6
9
10
SS
2000
Mean
4.49
6.55
8.86
12.91
10.20
16.41
16.78
19.38
37.31
17.86
66.44
39.20
76.28
11.82
SD
0.54
1.19
1.54
7.33
3.09
7.17
6.07
14.54
42.43
7.30
72.73
45.20
41.40
1.32
n†
10
10
10
10
10
9
9
10
10
10
7
9
3
10
SS
Test for significance
NS
NS
DN
U
NS
NS
NS
NS
NS
NS
NS
NS
U
DN
Abbreviations: DN: Duncan’s multiple range test; NS: not significant; SD: standard deviation; SS: statistical significance; U: Mann–Whitney U-test versus control. †Group “n”s were reduced for some weeks due to individual animals either having (0) weight gain or weight loss. ,.
