Research Article

Toxicological Investigations of Aristolochia longa Root Extracts

Table 1

Effect of ALAE on liver function (AST and ALT) in rats.

GroupsAST (UI/L)ALT (UI/L)
Day 6Day 11Day 16Day 21Day 6Day 11Day 16Day 21

Control100.8 ± 6.4101.32 ± 5.1280.0 ± 393.3 ± 6.622.8 ± 1.525.6 ± 3.132.2 ± 3.332.7 ± 1.1
G1134.6 ± 5.4107.9 ± 2.593.2 ± 0.4227.4 ± 6.236.6 ± 0.537.7 ± 2.544.6 ± 3.9086.3 ± 2.1
G2145.6 ± 1.30123.3 ± 0.287.7 ± 2.4130.8 ± 3.525.3 ± 2.6031.3 ± 2.129.7 ± 0.945.9 ± 1.4
G3122.5 ± 4.6139.4 ± 2.9106.0 ± 5.2117.1 ± 5.828.7 ± 1.135.4 ± 0.333.5 ± 1.734.9 ± 1.3
G4100.8 ± 2.9144.8 ± 5.394.8 ± 0.9107.1 ± 4.729.6 ± 0.634.2 ± 2.443.3 ± 2.133.4 ± 1.6
G5124.1 ± 3.4172.5 ± 3.892.0 ± 4.4189.5 ± 232.2 ± 1.944.0 ± 1.623.7 ± 2.087.3 ± 2.1

Values are expressed as mean ± SD, n = 2. compared to the control group. compared to the control group. compared to the control group. compared to the control group.