Research Article

Toxicological Investigations of Aristolochia longa Root Extracts

Table 2

Effect of ALAE on renal function (urea and creatinine) in rats.

GroupsUrea (g/L)Creatinine (mg/L)
Day 6Day 11Day 16Day 21Day 6Day 11Day 16Day 21

Control0.19 ± 0.010.26 ± 0.020.23 ± 0.020.23 ± 0.032.48 ± 0.042.51 ± 0.043.16 ± 0.093.07 ± 0.12
G10.20 ± 0.010.40 ± 00.20 ± 0.020.34 ± 0.043.94 ± 0.163.36 ± 0.273.26 ± 0.123.82 ± 0.08
G20.34 ± 0.020.32 ± 0.030.26 ± 0.010.40 ± 0.033.57 ± 0.054.97 ± 0.173.13 ± 0.163.13 ± 0.09
G30.29 ± 0.020.29 ± 0.020.41 ± 0.020.32 ± 0.033.76 ± 0.384.51 ± 0.033.49 ± 0.123.51 ± 1
G40.25 ± 0.010.25 ± 0.030.27 ± 0.030.29 ± 0.023.33 ± 0.213.21 ± 0.092.72 ± 0.085.31 ± 0.13
G50.37 ± 0.030.29 ± 0.020.26 ± 0.060.33 ± 0.033.67 ± 0.093.90 ± 0.083.33 ± 0.175.40 ± 0.03

Values are expressed as mean ± SD, n = 2. compared to the control group. compared to the control group. compared to the control group. compared to the control group.