Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts

Figure 3

Photomicrographs showing liver of rats. (a) Normal-the hepatocytes are normal morphologically and arranged in cords around blood vessels except that the limiting plate appears shrunken, (b) CCl₄ only-centrilobular coagulation necrosis of hepatocytes, (c) CCl₄ + Sily-moderate centrilobular hepatocellular vascular degeneration, restricted more to the zone 3 hepatocytes and a few regenerative hepatocytes, (d) CCl₄ +  DRR-diffuse hepatocellular atrophy, spotty hepatocellular necrosis, Kupffer cell hyperplasia, and moderate perivascular infiltrates in the portal tract, (e) Para only: Moderate centrilobular hepatocellular and cord atrophy, (f) Para + Sily: normal (no observable lesion), and (g) Para + DRR : LIVER- normal (no observable lesion).

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