Evaluation of the Acute Hepatoprotective Potential of Hydroethanolic Extract of Duranta erecta L. Parts

Table 3

Effect of treatment on liver oxidative stress parameters.

	Normal	CCl4 only	Para only	CCl4 + Sily	Para + Sily	CCl4 + DRR	Para + DRR
H2O2 (μmole/mg protein)	69.78 ± 6.74	99.06 ± 10.63^a	122.31 ± 17.37^a	110.17 ± 8.07^a	56.13 ± 3.13^c	65.58 ± 6.97^b	121.63 ± 16.79^a
MDA (μmole/mg protein)	3.59 ± 0.68	14.25 ± 1.46^a	14.82 ± 5.01^a	3.25 ± 2.29^b	3.01 ± 1.32^c	3.84 ± 2.36^b	3.94 ± 4.36^c
GSH (μmole/mg protein)	74.72 ± 2.34	72.44 ± 1.64	83.18 ± 6.07	78.52 ± 1.06	77.51 ± 2.70	78.34 ± 2.32	74.82 ± 2.27
GPx (μmole/mg protein)	713.82 ± 48.18	563.03 ± 24.57^a	682.95 ± 49.60	868.15 ± 71.57^b	1225.42 ± 37.90^c	906.05 ± 65.94^ab	1055.99 ± 42.72^ac
GST (µmole/min/mg protein)	1.07 ± 0.11	0.78 ± 0.12	1.22 ± 0.18	0.90 ± 0.19	0.91 ± 0.22	2.14 ± 1.0	2.63 ± 0.68
SOD (Units/mg protein)	25.28 ± 1.70	19.94 ± 0.84	25.83 ± 2.38	31.75 ± 2.48^b	43.88 ± 1.31^ac	32.60 ± 2.47^b	37.51 ± 1.05^ac
Nitric oxide (μmole/L)	0.98 ± 0.05	2.77 ± 0.47^a	0.98 ± 0.03	1.19 ± 0.16^b	0.49 ± 0.02	2.14 ± 0.16^a	2.53 ± 0.17^ac

Statistical Significance: ^a–0.001 from normal; ^b–0.001 from CCl₄ only; ^c–0.001 from Para only.