Larval Cytotoxic and Subacute Toxicity of Gardenia ternifolia, Rourea coccinea, and Cassytha filiformis Used in Traditional Medicine of Benin (West Africa)
Table 1
Effect of studied plants extracts on hematological parameters of rats in different lots.
Control
C. filiformis, 200 mg/kg
C. filiformis, 400 mg/kg
C. filiformis, 800 mg/kg
R. coccinea, 200 mg/kg
R. coccinea, 400 mg/kg
R. coccinea, 800 mg/kg
G. ternifolia, 200 mg/kg
G. ternifolia, 400 mg/kg
G. ternifolia, 800 mg/kg
RB (T/L)
7.33 ± 0.88
7.01 ± 1.27
7.71 ± 0.42
7.70 ± 0.55
7.44 ± 1.02
5.92 ± 2.40
5.48 ± 1.77
6.73 ± 1.03
6.67 ± 0.42
6.52 ± 1.68
Hb (g/dL)
14.44 ± 1.70
12.55 ± 1.98
14.3 ± 0.45
13.95 ± 0.65
13.67 ± 2.1
11.93 ± 3.92
10.57 ± 3.35
13.56 ± 0.19
15.07 ± 0.65
12.40 ± 1.27
Hte (%)
53 ± 1.73
43.25 ± 2.62
47.25 ± 1.25
47.5 ± 3.11
41.97 ± 4.20
38.23 ± 6.21
33.23 ± 11.33
50.25 ± 2.21
48.5 ± 3.69
47.75 ± 7.80
MGV (fL)
76.33 ± 15.69
62.75 ± 10.37
61.25 ± 4.03
62.25 ± 4.64
56.3 ± 5.02
70.83 ± 23.46
60.53 ± 4.55
78.25 ± 13.09
89.25 ± 2.5
74.75 ± 8.26
MCH (g/dL)
20 ± 5.29
18.25 ± 0.95
18.75 ± 0.5
18.5 ± 0.58
33.1 ± 2.08
30.6 ± 5.91
32.03 ± 1.25
20.75 ± 3.20
26.75 ± 2.36
20 ± 4.69
MCHC (pg)
27 ± 2.64
29.5 ± 3.69
30.5 ± 1.29
29.75 ± 1.25
18.23 ± 1.75
20.77 ± 2.30
19.37 ± 0.93
27 ± 0.81
31.25 ± 2.87
26.5 ± 3.87
WB (T/L)
9.97 ± 1.45
6.925 ± 1.54
9.45 ± 2.7
9.825 ± 1.75
8 ± 2.36
8.37 ± 2.28
10.6 ± 2.65
8.225 ± 4.22
8.4 ± 2.04
8.47 ± 3.89
PN (%)
26 ± 25.53
12.25 ± 10.71
19.25 ± 10.90
9.5 ± 3.87
14.63 ± 3.45
14.1 ± 2.42
11.53 ± 1.23
24.75 ± 14.38
24 ± 3.91
25.25 ± 16.96
Monocytes (%)
5.5 ± 4.95
2.75 ± 2.06
5.25 ± 2.63
3.75 ± 1.5
8.9 ± 7.00
3.63 ± 3.04
2.3 ± 3.16
5.5 ± 2.08
6.25 ± 1.71
5 ± 0.82
Lymphocyte (%)
69.67 ± 27.02
83.5 ± 14.47
72.5 ± 12.92
83.75 ± 5.67
76.47 ± 9.59
82.27 ± 4.72
86.17 ± 4.30
66.5 ± 15.80
47.75 ± 7.13
69.5 ± 17.82
RB, red blood cells; Hb, hemoglobin; Hte, hematocrit; MGV, mean globular volume; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; WB, white blood cell; PN, neutrophilic polynuclear. ∗Statistically significant.
