Protective Effect of Costus afer Aqueous Leaf Extract (CALE) on Low-Dose Heavy Metal Mixture-Induced Alterations in Serum Lipid Profile and Hematological Parameters of Male Wistar Albino Rats

Table 2

Effect of Costus afer on hematological parameters of male albino rats treated with metal mixture.

Treatment

T.WBC

NEU

LYM

MON

EOS

BAS

RBC

HGB

PCV

MCV

MCH

MCHC

PLT

Deionized H2O (only)

6.7 ± 1.87^a

63.4 ± 8.44^c

27.3 ± 6.81^a

5.0 ± 3.03^b

3.3 ± 1.58^b

1.1 ± 0.32^b

5.2 ± 0.19^d

13.4 ± 1.51^c

41.4 ± 3.76^d

79.4 ± 8.31^a

25.7 ± 2.96^a

32.8 ± 5.84^a

199.0 ± 40.99^a

Metal mixture (only)

15.0 ± 2.02^d

28.4 ± 4.32^a

69.8 ± 4.59^d

1.1 ± 0.34^a

0.4 ± 0.05^a

0.3 ± 0.08^a

3.1 ± 0.15^a

8.6 ± 1.07^a

25.2 ± 3.14^a

81.7 ± 9.54^ab

28.0 ± 3.23^a

34.8 ± 6.77^a

219.0 ± 43.70^a

Metal mixture + 750 mg/kg

12.2 ± 1.41^c

35.2 ± 2.05^a

62.3 ± 2.19^c

1.3 ± 0.08^a

0.7 ± 0.07^a

0.6 ± 0.13^a

3.4 ± 0.19^b

10.0 ± 0.85^ab

30.9 ± 1.05^b

90.6 ± 6.92^b

29.3 ± 2.74^a

32.3 ± 2.28^a

210.0 ± 18.37^a

Metal mixture + 1500 mg/kg

9.6 ± 0.42^b

43.4 ± 2.39^b

52.7 ± 2.29^b

1.8 ± 0.11^a

1.1 ± 0.27^a

0.9 ± 0.21^b

4.1 ± 0.30^c

11.8 ± 1.69^bc

36.1 ± 1.66^c

89.5 ± 8.85^ab

29.2 ± 5.57^a

32.6 ± 4.73^a

206.0 ± 20.74^a

Metal mixture + 2250 mg/kg

6.8 ± 1.22^a

61.0 ± 8.54^c

28.9 ± 7.46^a

5.3 ± 1.73^b

3.6 ± 0.75^b

1.1 ± 0.36^b

5.3 ± 0.21^d

13.4 ± 1.79^c

41.2 ± 2.02^d

78.4 ± 5.07^a

25.5 ± 3.71^a

32.4 ± 3.02^a

204.0 ± 19.81^a

Values are expressed as (mean ± SD, N = 5). In each column, values with different superscripts (a, b, and c) are significantly different from each other () and those with the same superscripts are not significantly different.