Clerodendrum volubile Ethanol Leaf Extract: A Potential Antidote to Doxorubicin-Induced Cardiotoxicity in Rats

Table 7

Effect of repeated oral treatment with 50–400 mg/kg/day of CVE on the average body weight of DOX-treated rats.

Group	Body wt. on day 1 (g)	Body wt. on day 14	% ∆wt.
I	159.9 ± 15.1	143.1 ± 19.0	−10.7 ± 04.7^c−
II	178.3 ± 18.0	191.1 ± 20.6	07.1 ± 04.1^c+
III	144.2 ± 15.8	141.5 ± 25.2	−02.4 ± 10.5^a+
IV	163.9 ± 08.0	153.0 ± 11.0	−06.6 ± 04.8^a+
V	154.0 ± 19.6	151.6 ± 23.1	09.0 ± 05.5^c+
VI	165.2 ± 12.4	147.9 ± 12.8	−10.6 ± 05.8
VII	151.3 ± 12.9	146.0 ± 15.4	−03.5 ± 04.5^a+
VIII	163.8 ± 16.8	187.4 ± 20.2	14.5 ± 06.2

^c−A significant decrease at when compared to the untreated (normal) negative control (Group VIII). ^c+A significant increase at when compared to the untreated (DOX-treated) negative control (Group I). ^a+A significant increase at when compared to the untreated (DOX-treated only) negative control (Group I).