Cytotoxicity Potential of Endophytic Fungi Extracts from Terminalia catappa against Human Cervical Cancer Cells

Table 2

Anticancer screening of endophytic fungi extracts on uterine cervical cancer cells (HeLa). The anticancer activity was determined via MTT assay after exposure to metabolite extracts for 48 h.

Code	HeLa cells
	IC50 (µg/ml)
N8	NC
N97	33.35
N223	136.80
N169	149.20
N2	175.80
N7	NC

The IC₅₀ values were determined using GraphPad Prism. , , significantly different from control. Samples were compared using One-Way ANOVA and Tukey comparison of all pairs of columns. IC₅₀: extract concentration required to reduce HeLa cancer cell line by 50%. N97: endophytic extracts from stem bark of Terminalia catappa; N169: endophytic extracts from twigs of Terminalia mantaly; N2: endophytic extracts from stem of Cananga odorata; N8: endophytic extracts from leaves of Cananga odorata; N233: endophytic extracts from leaves of Terminalia mantaly. NC: none converged.