Nanonaringenin and Vitamin E Ameliorate Some Behavioral, Biochemical, and Brain Tissue Alterations Induced by Nicotine in Rats

Figure 4

A higher magnification of brain tissue in adult male albino rats showing the groups. (a) Control group, showing normal nerve cells with a large spherical vesicular nucleus and basophilic cytoplasm (arrow). The neuroglia cells (arrow head) appeared normal and adjacent to the neurons. (b) N group, the majority of nerve cells appeared degenerated (arrow) the neuroglia cells (arrow head) appeared suffering from degeneration and necrosis. (c) NNG group, both nerve cells (arrow) and neuroglia (arrow head) appeared normal. (d) N + E group, nerve cells appeared normal (arrow) while other neurons suffered from degeneration (arrow head). (e) N + NNG group, the majority of neurons seemed to be normal (arrow) and the neuroglia cells appeared normal around neurons. (f) N + NNG + E group, the neurons (arrow) and the neuroglia cells appeared normal. H&E stain X 400.

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