Protective Effects of Hydroalcoholic Extract of Rosa canina Fruit on Vancomycin-Induced Nephrotoxicity in Rats

Figure 2

Photomicrograph of rat kidney stained with hematoxylin and eosin (10x). (A) Control. (B) Vancomycin (VAN) treated. (C) VAN plus 250 mg/kg hydroalcoholic extract of Rosa canina. (D) VAN plus 500 mg/kg hydroalcoholic extract of Rosa canina. (E) Only 500 mg/kg hydroalcoholic extract of Rosa canina. In the VAN group, diffuse tubular dilatation (large arrow) and casts (small arrow) are prominent at this picture. There are also areas of necrosis and inflammation. All of these changes are less prominent or absent in VAN + RC groups in C and D.