A 90-Day Oral Toxicity of Hydroethanolic Root Extract of Carissa spinarum in Wistar Rats

Table 1

Effect of the hydroethanolic extract of Carissa spinarum root on rats’ body weight.

Weeks	Hydroethanolic root extract of C. spinarum
	Control	500 mg/kg	1000 mg/kg
0	159.58 ± 8.51	163.16 ± 7.48	160.41 ± 7.73
1	160.33 ± 7.49	158.75 ± 7.65	162.91 ± 5.14
2	160.16 ± 8.41	164.50 ± 7.30	164.58 ± 5.37
3	163.00 ± 8.36	165.91 ± 8.16	165.00 ± 5.73
4	170.91 ± 8.82	171.33 ± 8.46	170.00 ± 6.25
5	172.83 ± 8.35	175.09 ± 7.78	171.63 ± 6.07
6	178.83 ± 7.87	180.54 ± 8.90	176.60 ± 7.48
7	175.58 ± 7.69	183.00 ± 9.18	176.30 ± 6.89
8	175.41 ± 7.67	186.00 ± 9.10	179.40 ± 6.54
9	175.50 ± 7.72	178.88 ± 7.84	178.70 ± 6.50
10	175.45 ± 8.55	179.62 ± 7.99	179.00 ± 6.20
11	186.50 ± 9.97	179.87 ± 9.17	177.50 ± 5.19
12	184.20 ± 10.93	189.66 ± 8.44	169.50 ± 7.65
13	188.77 ± 12.77	194.00 ± 11.26	177.75 ± 7.39

Each value is a mean ± SEM, n = 8.