A 90-Day Oral Toxicity of Hydroethanolic Root Extract of Carissa spinarum in Wistar Rats

Table 4

Effect of the hydroethanolic extract of Carissa spinarum root on biochemical parameters.

Parameters		Hydroethanolic root extract of C. spinarum
	Control	500 mg/kg	1000 mg/kg
Glucose, mmol/L	5.13 ± 0.36	5.10 ± 0.34	4.38 ± 0.32
ALAT, UI/L	40.91 ± 5.72	38.62 ± 4.29	38.95 ± 5.47
ASAT, UI/L	160.33 ± 6.20	174.35 ± 9.04	160.78 ± 6.68
ALP, UI/L	316.88 ± 31.83	352.67 ± 35.70	235.19 ± 33.75
Urea, g/L	0.49 ± 0.03	0.48 ± 0.05	0.41 ± 0.02
Creatinine, g/dL	4.29 ± 0.33	3.20 ± 025	3.50 ± 0.21
CPK	338.29 ± 31.83	339.39 ± 46.82	261.06 ± 28.35
Triglycerides, g/L	1.59 ± 0.11	1.75 ± 0.16	1.64 ± 0.09
Sodium, mmol/L	192.56 ± 2.85	173.93 ± 11.86	189.66 ± 9.81
Potassium, mmol/L	2.08 ± 0.14	1.66 ± 0.19	1.84 ± 0.18
Chloride, mmol/L	79.20 ± 3.83	87.23 ± 2.48	108.42 ± 8.30
Calcium, mg/dL	8.28 ± 0.37	7.11 ± 0.44	8.02 ± 0.38

Each value is a mean ± SEM, n = 8. .