Effect of Azadirachta indica and Senna siamea Decoction on CD4+ and CD8+ Level, Toxicological, and Antioxidant Profile in HIV/AIDS Positive Persons

Table 3

Variation of LT CD4+ and LT CD8+ in different groups.

Period	Parameters	Group 1; N  = 97	Group 2; N  = 100	Group 3; N  = 100	value	ODD
Day 0	CD4+	381 ± 12	357 ± 13	328 ± 11	0.4	0.973 (0.742–1.104)
	CD8+	1382 ± 49	1279 ± 56	1373 ± 42	0.1	0.871 (0.714–1.001)
	CD4+/CD8+	0.27 ± 0.03	0.28 ± 0.02	0.24 ± 0.02	0.1	1.028 (0.804–1.111)
After 6 months	CD4+	501 ± 24^a	549 ± 22^a	752 ± 14^b	0.01	1.634 (0.931–2.042)
	CD8+	1407 ± 47	1007 ± 56	1026 ± 41	0.1	1.004 (0.847–1.135)
	CD4+/CD8+	0.37 ± 0.03^a	0.54 ± 0.0.04^b	0.73 ± 0.04^c	0.02	1.719 (1.082–2.109)

Group 1, decoction; Group 2, ART; Group 3, ART + decoction. Results are expressed in means ± SEM; a, b, and c indicate the statistical differences of Tukey’ posthoc test; statistically significant (, one-way ANOVA of groups 1, 2, and 3).