Research Article

Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Table 5

Changes in litter weights from female rats administered with UNCP for 15 days prior to mating.

GroupSexPostnatal days (PND)
4th day7th day14th day21st day28th day

Cocoa HD6.61 ± 0.239.58 ± 0.3121.17 ± 0.6330.04 ± 1.6553.32 ± 3.14
6.67 ± 0.3310.44 ± 0.3122.64 ± 0.6332.77 ± 1.7760.95 ± 3.49

Cocoa TD7.44 ± 0.5211.89 ± 1.0123.14 ± 1.6435.57 ± 1.8958.41 ± 3.26
7.83 ± 0.3511.79 ± 0.5723.68 ± 1.2536.40 ± 1.5864.36 ± 4.09

Vehicle control8.27 ± 0.3312.53 ± 0.6625.13 ± 0.8536.53 ± 1.1963.42 ± 3.95
8.76 ± 0.4413.12 ± 0.7825.96 ± 1.1537.06 ± 1.6068.72 ± 2.32