Research Article

Reproductive Toxicity of Theobroma cacao: Increase in Survival Index, Nongenotoxic, and Proimplantation Potential

Table 9

Reproductive function of female rats crossed with males that received UNCP for 48 days before mating.

DosesQuantity/amount per femalePreimplantation loss, %Postimplantation loss, %
Corpora luteaNumber of implantsViable fetuses/full-term pups

Cocoa HD15.88 ± 0.5214.13 ± 0.6910.25 ± 2.2410.56 ± 4.4329.93 ± 13.98
Cocoa TD14.89 ± 0.5913.44 ± 0.6912.44 ± 0.779.55 ± 3.656.96 ± 4.16
Vehicle control15.90 ± 0.8712.70 ± 1.3612.30 ± 1.3421.04 ± 7.472.87 ± 1.92
Historical control14.13 ± 0.8813.00 ± 1.0912.00 ± 1.218.44 ± 3.938.49 ± 2.80