Toxicological Profile of the Aqueous Extract of Tectona grandis L.F. (Verbenaceae) Leaves: A Medicinal Plant Used in the Treatment of Typhoid Fever in Traditional Cameroonian Medicine

Table 7

Effect of aqueous extract of T. grandis leaves on lipid profile of animals.

Groups	Triglycerides (mg/dL)	T-cholesterol (mg/dL)	HDL (mg/dL)	LDL (mg/dL)	HDL/LDL ratio	Atherogenic index
Males
Control	87.96 ± 3.05^a	79.70 ± 6.57^a	39.94 ± 7.10^a	22.17 ± 7.29^ab	2.09 ± 1.26^a	1.03 ± 0.31^b
30 mg/kg	87.04 ± 5.72^a	116.34 ± 11.18^cd	57.79 ± 14.58^ab	41.14 ± 6.94^c	1.46 ± 0.52^a	1.08 ± 0.36^b
90 mg/kg	104.63 ± 14.02^b	89.72 ± 5.79^ab	59.09 ± 14.01^ab	9.70 ± 1.27^a	8.34 ± 1.83^b	0.54 ± 0.17^a
270 mg/kg	117.59 ± 3.16^b	123.05 ± 10.84^d	67.42 ± 10.14^b	32.11 ± 10.83^bc	2.29 ± 0.78^a	0.85 ± 0.29^ab
810 mg/kg	84.48 ± 6.95^a	100.00 ± 6.82^bc	53.57 ± 6.55^ab	29.53 ± 4.83^bc	1.86 ± 0.42^a	0.88 ± 0.17^ab
Females
Control	74.81 ± 6.23^a	61.15 ± 7.20^a	32.14 ± 2.63^a	14.04 ± 7.75^a	2.91 ± 1.52^b	0.91 ± 0.24^a
30 mg/kg	100.37 ± 7.37^b	102.71 ± 14.19^b	59.63 ± 8.17^b	23.00 ± 2.99^ab	2.71 ± 1.18^ab	0.79 ± 0.31^a
90 mg/kg	64.44 ± 5.41^a	97.94 ± 10.96^b	44.74 ± 1.87^ab	40.31 ± 12.50^c	1.20 ± 0.43^ab	1.19 ± 0.28^ab
270 mg/kg	91.30 ± 11.40^b	86.36 ± 9.83^b	36.26 ± 5.14^a	31.85 ± 6.45^bc	1.17 ± 0.27^a	1.40 ± 0.33^b
810 mg/kg	92.04 ± 4.93^b	87.88 ± 4.08^b	46.00 ± 6.49^ab	23.48 ± 4.82^ab	2.09 ± 0.84^ab	0.93 ± 0.20^ab

Data are expressed as mean ± SD, n = 4. Values for a given group in a column followed by a different letter as superscript are significantly different according to Waller–Duncan’s multiple comparison test ( < 0.05). HDL: high-density lipoprotein; LDL: low-density lipoprotein; AI: Atherogenic index; T-Chol: total cholesterol.