Protective Effect of Hydroalcoholic Extract of Stachys pilifera on Oxidant-Antioxidant Status in Renal Ischemia/Reperfusion Injuries in Male Rats

Table 1

Effects of Stachys pilifera extract on renal function parameters.

Groups	SC	IR	IR + SP
KW (gr)	1.07 ± 0.05	1.09 ± 0.05	1.23 ± 0.02
UV (mL)	0.015 ± 0.000	0.012 ± 0.002	0.011 ± 0.001
V^° (mL/min gKW)	0.014 ± 0.000	0.010 ± 0.001	0.013 ± 0.002
PNa (mmol/L)	146.35 ± 2.58	147.60 ± 1.53	147.11 ± 1.44
PK (mmol/L)	4.27 ± 0.12	4.03 ± 0.16	3.99 ± 0.11
PCr (mg/dL)	0.65 ± 0.01	1.53 ± 0.05	1.16 ± 0.25
Purea (mg/dL)	20.45 ± 1.53	50.25 ± 5.66	50.77 ± 11.16
UCr (mg/dL)	74.55 ± 6.60	46.55 ± 1.81	101.10 ± 22.05
Uurea (mg/dL)	1368.66 ± 60.54	1196.66 ± 89.98	1873.83 ± 526.57
UNaV^° (μmol/min. gKW)	0.36 ± 0.02	0.94 ± 0.17	0.60 ± 0.18
UKV^° (μmol/min. gKW)	0.22 ± 0.01	1.30 ± 0.20	0.80 ± 0.24

Effect of SP extract on some biochemical markers following I/R injury. Data are shown as mean ± SEM. Significant against the SC group (); ^#significant against the I/R rats (). SP: Stachys pilifera; SC: sham control; I/R: ischemia/reperfusion; KW: kidney weight; UV: urine volume; V^°: urine flow rate; PK: plasma K; PNa: plasma Na; Purea: plasma urea; PCr: plasma creatinine; UCr: urine creatinine; Uurea: urine urea; UNaV^°: absolute excretion of Na; UKV^°: absolute excretion of K.